Home-based respiratory-gated transcutaneous auricular vagus nerve stimulation for rheumatoid arthritis—a feasibility study
An adequately powered, randomised controlled trial of home-based respiratory-gated taVNS in people with rheumatoid arthritis is feasible and safe. Key Points • To the best of our knowledge, this study is the first to evaluate the feasibility of homebased respiratory-gated (RG) transcutaneous auricular vagus nerve stimulation (taVNS) for the treatment of rheumatoid arthritis (RA). • Feasibility outcomes demonstrated high adherence and excellent usability ratings with few treatment-emergent adverse events reported. • Home-based RG taVNS using the developed system is safe and feasible to evaluate in an adequately powered, controlled trial.
Authors
- Gwyn N. Lewis (ORCID: https://orcid.org/0000-0001-9324-0940)
- Wee‐Leong Chang (ORCID: https://orcid.org/0000-0002-9675-9737)
- Faisal Almesfer (ORCID: https://orcid.org/0000-0002-5924-0135)
- M. T. Kluger (ORCID: https://orcid.org/0000-0003-0842-7298)
- K. P. L. Ng
- Ankit Parikh
- Hamid GholamHosseini
- David Rice
Institutions
- University of Auckland (NZ)
- North Shore Hospital (NZ)
- Auckland University of Technology (NZ)
- Waitemata District Health Board (NZ)
Publication Details
- Journal
- Clinical Rheumatology
- Published
- 2026-03-23
- DOI
- https://doi.org/10.1007/s10067-026-08041-x
- Primary Topic
- Vagus Nerve Stimulation Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00