A cancer neuroscience-related gene model for prognosis prediction and immunotherapy response evaluation in breast cancer

This study establishes and validates a novel 12-gene cancer neuroscience-related prognostic model for breast cancer. This model not only effectively stratifies patient risk but also reveals distinct immune landscapes and predicts differential responses to immunotherapy and potential therapeutic agents. These findings offer new insights for prognostication and personalized treatment strategies in breast cancer.

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Publication Details

Journal
Discover Oncology
Published
2026-03-22
DOI
https://doi.org/10.1007/s12672-026-04906-4
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

A cancer neuroscience-related gene model for prognosis prediction and immunotherapy response evaluation in breast cancer

Mengyang Li, Yansha Wei, Caixin Qiu, Jiehua Li
Discover Oncology
Ferroptosis and cancer prognosis
article

A cancer neuroscience-related gene model for prognosis prediction and immunotherapy response evaluation in breast cancer

Mengyang Li, Yansha Wei, Caixin Qiu, Jiehua Li
article en

Abstract

This study establishes and validates a novel 12-gene cancer neuroscience-related prognostic model for breast cancer. This model not only effectively stratifies patient risk but also reveals distinct immune landscapes and predicts differential responses to immunotherapy and potential therapeutic agents. These findings offer new insights for prognostication and personalized treatment strategies in breast cancer.

Discover Oncology
The People's Hospital of Guangxi Zhuang Autonomous Region (CN), First Affiliated Hospital of GuangXi Medical University (CN)
Good health and well-being
Openalex Percentile: Top 14%
Ferroptosis and cancer prognosis
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