Process Development and Intensification of Chemical Reaction

The chemical industries are pivotal to the modern world and works to convert raw materials such as oil painting, natural gas, air, water, essence, and minerals into more than 70,000 different products. These base products are also used to make consumer products in addition to manufacturing, service, construction and other. The process of the organic chemicals by using a zero waste discharge technology and the solvent recovery to make a green reaction, which is economically feasible as well grounded on the conception of waste management by using the different types of catalyst and studying the part catalyst in the reaction. In the upstream reaction an amidation reaction is developed here in the project of the pharmaceutical intermediate or product which is extensively used in chemical and pharmaceuticals. The use of the zero valent palladiumnano catalyst system for amidation of aryl halides which has not been efficiently proved. The reaction is well liberalized toward a variety of functional aryl halides and a wide range of aromatic and aliphatic primary amides in good to excellent yields. Nanoparticles having extraordinarily large surface area and huge number of active sites in comparison to bulk material act as effective catalyst for organic synthesis.