Dried Serum Spots for External Quality Assurance of Scrub Typhus <scp>IgM</scp> Serology: A Multicentre Pilot Study From India

Dried serum spots are a feasible, reliable and cost-effective alternative to conventional liquid serum for external quality assurance of O. tsutsugamushi IgM ELISA. The initial discordance observed underscores the importance of EQA in identifying procedural variability, while the final concordance confirms the robustness and suitability of DSS for EQA implementation in resource-limited, endemic settings like India.

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Publication Details

Journal
Tropical Medicine & International Health
Published
2026-03-22
DOI
https://doi.org/10.1111/tmi.70132
Primary Topic
Vector-borne infectious diseases
Type
article
Field-Weighted Citation Impact
0.00
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Dried Serum Spots for External Quality Assurance of Scrub Typhus IgM Serology: A Multicentre Pilot Study From India

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Dried Serum Spots for External Quality Assurance of Scrub Typhus IgM Serology: A Multicentre Pilot Study From India

Haripriya Sivakumar, Ferdinamarie Sharmila Philomenadin, Ratchagadasse Vimal Raj, Dinakaran Vasudevan, Harmanmeet Kaur, Rahul Dhodapkar
article en

Abstract

Dried serum spots are a feasible, reliable and cost-effective alternative to conventional liquid serum for external quality assurance of O. tsutsugamushi IgM ELISA. The initial discordance observed underscores the importance of EQA in identifying procedural variability, while the final concordance confirms the robustness and suitability of DSS for EQA implementation in resource-limited, endemic settings like India.

Tropical Medicine & International Health
Amity University (IN), Jawaharlal Institute of Post Graduate Medical Education and Research (IN)
Partnerships for the goals
Openalex Percentile: Top 11%
Vector-borne infectious diseases
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