Microscopic colitis and primary sclerosing cholangitis are bidirectionally associated: A nationwide matched cohort and case–control study

This nationwide study reveals a bidirectional association between MC and PSC. Although absolute risks are low, these findings suggest that MC may have diagnostic relevance in suspected PSC cases, and vice versa. Physicians treating MC patients should be alert to signs and symptoms of PSC.

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Publication Details

Journal
Journal of Internal Medicine
Published
2026-03-22
DOI
https://doi.org/10.1111/joim.70084
Primary Topic
Microscopic Colitis
Type
article
Field-Weighted Citation Impact
0.00
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article

Microscopic colitis and primary sclerosing cholangitis are bidirectionally associated: A nationwide matched cohort and case–control study

Björn Lindkvist, Charlotte Hedin, Jiangwei Sun, D. K. Bergman et al.
Journal of Internal Medicine
Microscopic Colitis
article

Microscopic colitis and primary sclerosing cholangitis are bidirectionally associated: A nationwide matched cohort and case–control study

Björn Lindkvist, Charlotte Hedin, Jiangwei Sun, D. K. Bergman, J Yao, Anders Forss, Hannes Hagström, Fahim Ebrahimi, Annika Bergquist, Jonas F. Ludvigsson
article en

Abstract

This nationwide study reveals a bidirectional association between MC and PSC. Although absolute risks are low, these findings suggest that MC may have diagnostic relevance in suspected PSC cases, and vice versa. Physicians treating MC patients should be alert to signs and symptoms of PSC.

Journal of Internal Medicine
Karolinska University Hospital (SE), Sahlgrenska University Hospital (SE), University Hospital of Basel (CH), Karolinska Institutet (SE), Örebro University Hospital (SE), Columbia University (US)
Good health and well-being
Openalex Percentile: Top 16%
Microscopic Colitis
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Microscopic colitis and primary sclerosing cholangitis are bidirectionally associated: A nationwide matched cohort and case–control study — Björn Lindkvist, Charlotte Hedin, et al. · Journal of Internal Medicine (2026) | TGRS Research Map | TGRS