Antiretroviral Therapy Switching Among People with HIV in the United States is not Uncommon Despite Virologic Suppression: An OPERA Cohort Study
In this large, contemporary US cohort, ART regimen switching was somewhat common and most frequently occurred among virologically suppressed PWH. These real-world findings on the incidence and patterns of virologically suppressed switches provide insight into new trends in treatment optimization and the need for new therapeutic options.
Authors
- Michael Sension
- Jennifer S Fusco (ORCID: https://orcid.org/0000-0003-1556-811X)
- Michael D. Osterman (ORCID: https://orcid.org/0000-0003-4302-6596)
- Gerald Pierone (ORCID: https://orcid.org/0000-0003-0159-7243)
- Laurence Brunet (ORCID: https://orcid.org/0000-0001-8467-4835)
- Girish Prajapati
- Gregory Fusco (ORCID: https://orcid.org/0000-0002-6834-784X)
- Sean P. Fleming
- Ricky K. Hsu
- Karam Mounzer
- Anthony M. Mills
Institutions
- Meridian Institute (US)
- Merck & Co., Inc., Rahway, NJ, USA (United States) (US)
- AIDS Healthcare Foundation (US)
- Fayetteville State University (US)
- NYU Langone Health (US)
- Oyster Point Family Health Center (US)
- International Myeloma Foundation (US)
- Philadelphia Fight (US)
Publication Details
- Journal
- Infectious Diseases and Therapy
- Published
- 2026-03-22
- DOI
- https://doi.org/10.1007/s40121-026-01334-3
- Primary Topic
- HIV/AIDS drug development and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00