Exposure to Antipsychotics in Youths at Clinical High Risk for Psychosis: Low <scp>VS</scp> High Doses and Their Relevance for Clinical Outcomes

APs at low doses are associated with better symptomatic outcomes, whilst APs at high doses correlate to poorer socio-occupational functioning. Promoting personalised treatment strategies and facilitating the identification of specific CHR-P subgroups with divergent prognoses are recommended in clinical practise.

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Publication Details

Journal
Early Intervention in Psychiatry
Published
2026-03-22
DOI
https://doi.org/10.1111/eip.70167
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Exposure to Antipsychotics in Youths at Clinical High Risk for Psychosis: Low VS High Doses and Their Relevance for Clinical Outcomes

Emanuela Leuci, Clara Pellegrini, Pietro Pellegrini, Derna Palmisano et al.
Early Intervention in Psychiatry
Schizophrenia research and treatment
article

Exposure to Antipsychotics in Youths at Clinical High Risk for Psychosis: Low VS High Doses and Their Relevance for Clinical Outcomes

Emanuela Leuci, Clara Pellegrini, Pietro Pellegrini, Derna Palmisano, Emanuela Quattrone, Alessandro Di Lisi, G. Paulillo, Marco Menchetti, Simona Pupo, Lorenzo Pelizza
article en

Abstract

APs at low doses are associated with better symptomatic outcomes, whilst APs at high doses correlate to poorer socio-occupational functioning. Promoting personalised treatment strategies and facilitating the identification of specific CHR-P subgroups with divergent prognoses are recommended in clinical practise.

Early Intervention in PsychiatryVol. 20(4)
Azienda Unita' Sanitaria Locale di Parma (IT), Ospedale di Parma (IT), University of Bologna (IT)
No poverty
Openalex Percentile: Top 23%
Schizophrenia research and treatment
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