Association Between Emergency Department Mean Platelet Volume and Angiographic Severity in Unstable Angina: A Prognostic Study

ObjectiveMean platelet volume (MPV) has been associatedwith thrombotic risk and acute coronary syndrome(ACS) severity in various clinical settings. However,data regarding its prognostic value in unstable angina(UA) patients presenting to the emergency department(ED) are limited. This study aimed to investigate therelationship between MPV measured at ED admissionand the angiographic severity of ACS, as quantified bythe Gensini score, in patients with UA. A secondaryobjective was to assess the predictive value of MPVfor all-cause mortality.Material and MethodThis retrospective cohort study included 203 patientsdiagnosed with ACS between July 2022 and July 2023.MPV and other laboratory parameters were recordedat the time of admission. Coronary angiographyfindings were evaluated using the Gensini scoringsystem. Data were analyzed based on Gensini scorecategories and mortality status.ResultsMPV values were significantly higher in patients withhigh Gensini scores and in those who experiencedmortality (p