Female Sexual Dysfunction Induced by Second-Generation Antipsychotic Drugs—A Disproportionality Analysis Based on the FAERS Database

This pharmacovigilance study highlights significant associations between specific SGAs and female sexual dysfunction. Disproportionality signals vary by drug, symptom type, and prolactin-related mechanisms. Clinicians should consider sexual side effects in treatment decisions and monitor patients accordingly. Further prospective studies are warranted.

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Publication Details

Journal
Schizophrenia Bulletin
Published
2025-11-24
DOI
https://doi.org/10.1093/schbul/sbaf221
Primary Topic
Sexual function and dysfunction studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Female Sexual Dysfunction Induced by Second-Generation Antipsychotic Drugs—A Disproportionality Analysis Based on the FAERS Database

Dongdong Wang, Liuyin Jin, Linman Wu, Yu Cao
Schizophrenia Bulletin
Sexual function and dysfunction studies
article

Female Sexual Dysfunction Induced by Second-Generation Antipsychotic Drugs—A Disproportionality Analysis Based on the FAERS Database

Dongdong Wang, Liuyin Jin, Linman Wu, Yu Cao
article en

Abstract

This pharmacovigilance study highlights significant associations between specific SGAs and female sexual dysfunction. Disproportionality signals vary by drug, symptom type, and prolactin-related mechanisms. Clinicians should consider sexual side effects in treatment decisions and monitor patients accordingly. Further prospective studies are warranted.

Schizophrenia BulletinVol. 52(2)
North Sichuan Medical University (CN), Ningbo No. 2 Hospital (CN), Lishui City People's Hospital (CN), Baoshan University (CN), Nanchong Central Hospital (CN)
Gender equality
Openalex Percentile: Top 24%
Sexual function and dysfunction studies
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