Hydrodynamic behaviour of anti-reflux needle-free connectors during microinfusion with syringe pump: A bench-top study

Neutral displacement NFCs equipped with anti-reflux valves did not show evidence of altered infusion regularity under the experimental conditions tested. The results of this study suggest that using anti-reflux NFCs for the continuous delivery of drugs with a narrow therapeutic range may be considered compatible with low-flow infusion under controlled experimental conditions. This study represents a preliminary step toward further investigations on anti-reflux NFCs during syringe pump infusion and changeover.

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Publication Details

Journal
The Journal of Vascular Access
Published
2026-03-21
DOI
https://doi.org/10.1177/11297298261429548
Primary Topic
Central Venous Catheters and Hemodialysis
Type
article
Field-Weighted Citation Impact
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article

Hydrodynamic behaviour of anti-reflux needle-free connectors during microinfusion with syringe pump: A bench-top study

Serena Tupputi, Ilaria Ferrentino, A. Alberti, Stefano Elli et al.
The Journal of Vascular Access
Central Venous Catheters and Hemodialysis
article

Hydrodynamic behaviour of anti-reflux needle-free connectors during microinfusion with syringe pump: A bench-top study

Serena Tupputi, Ilaria Ferrentino, A. Alberti, Stefano Elli, Elisa Belotti, Sabrina Impaziente, Alberto Lucchini, Giulia Valagussa, Matilde Moriggi
article en

Abstract

Neutral displacement NFCs equipped with anti-reflux valves did not show evidence of altered infusion regularity under the experimental conditions tested. The results of this study suggest that using anti-reflux NFCs for the continuous delivery of drugs with a narrow therapeutic range may be considered compatible with low-flow infusion under controlled experimental conditions. This study represents a preliminary step toward further investigations on anti-reflux NFCs during syringe pump infusion and changeover.

The Journal of Vascular Access
Intensive Care Foundation (AU), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT), Ospedale Maggiore (IT), Azienda Ospedaliera San Gerardo (IT), Azienda Ospedaliera di Desio e Vimercate (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), University of Milano-Bicocca (IT)
Openalex Percentile: Top 22%
Central Venous Catheters and Hemodialysis
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