Autologous platelet-rich plasma versus hyaluronic acid, corticosteroids or saline for knee osteoarthritis: can blood draw volume serve as a proxy for platelet dose? A systematic review and meta-analysis
PRP provides superior patient-reported pain and function outcomes compared with HA, CS, and NS through six months, with benefits maintained to twelve months versus HA and CS in longer-term trials. Blood-draw volume may be a useful alternate when platelet dose is unreported.
Authors
- Alessandra Pelle (ORCID: https://orcid.org/0000-0002-1193-4875)
- Christopher J. Centeno
- Dustin R. Berger
- Ehren Dodson (ORCID: https://orcid.org/0000-0002-5808-6068)
- Ph. Hernigou
- Matthew B. Murphy
Institutions
- Université Paris-Est Créteil (FR)
- Broomfield Hospital (GB)
- RegeneRx Biopharmaceuticals (United States) (US)
- Hôpitaux Universitaires Henri-Mondor (FR)
- Talaris Therapeutics (United States) (US)
- Centeno-Schultz Clinic (US)
Publication Details
- Journal
- International Orthopaedics
- Published
- 2026-03-21
- DOI
- https://doi.org/10.1007/s00264-026-06782-7
- Primary Topic
- Periodontal Regeneration and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00