Functional response, in T2 severe asthmatic patients, treated with mepolizumab for 2 years

The increase in FEV1 observed in this cohort of patients shows that functional response is already detectable in the first two months of treatment. These clinical and functional improvements were sustained over two years of biologic therapy, even as pharmacologic treatment-particularly systemic corticosteroids-was progressively reduced.

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Publication Details

Journal
Journal of Asthma
Published
2026-03-21
DOI
https://doi.org/10.1080/02770903.2026.2645698
Primary Topic
Asthma and respiratory diseases
Type
article
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article

Functional response, in T2 severe asthmatic patients, treated with mepolizumab for 2 years

Manlio Milanese, Ludovica Napoli, Diego Bagnasco, Marco Bonavia et al.
Journal of Asthma
Asthma and respiratory diseases
article

Functional response, in T2 severe asthmatic patients, treated with mepolizumab for 2 years

Manlio Milanese, Ludovica Napoli, Diego Bagnasco, Marco Bonavia, Benedetta Bondi
article en

Abstract

The increase in FEV1 observed in this cohort of patients shows that functional response is already detectable in the first two months of treatment. These clinical and functional improvements were sustained over two years of biologic therapy, even as pharmacologic treatment-particularly systemic corticosteroids-was progressively reduced.

Journal of Asthma
Azienda Ospedaliera S.Maria (IT), Pulmonary Associates (US), Ospedale Santa Corona (IT), University of Genoa (IT)
Good health and well-being
Openalex Percentile: Top 13%
Asthma and respiratory diseases
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