Beyond the Metal: Sustained Efficacy and Diagnostic Nuances of Bioresorbable Coronary Scaffolds

Bioresorbable vascular scaffolds offer temporary mechanical support and local drug delivery to coronary arteries, ultimately restoring native vessel physiology after resorption. This case describes a 62-year-old man who underwent percutaneous coronary intervention with a second-generation sirolimus-eluting MeRes100 scaffold for significant proximal left anterior descending artery stenosis. Four years post-implantation, the patient remained asymptomatic but presented with intermittent, atypical chest pain. Coronary computed tomography angiography revealed complete scaffold resorption and preserved vessel patency, though interpretation was complicated by blooming artefacts from residual metallic markers. Second-generation scaffolds like MeRes100 show improved mechanical properties, predictable bioresorption profiles, and excellent clinical outcomes, including low rates of thrombosis and restoration of vasomotion. This case highlights both the long-term safety and efficacy of MeRes100 and the limitations posed by imaging artefacts, emphasizing the need for cautious computed tomography interpretation after scaffold resorption.

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Publication Details

Journal
Indian Journal of Clinical Cardiology
Published
2026-03-21
DOI
https://doi.org/10.1177/26324636261431069
Primary Topic
Coronary Interventions and Diagnostics
Type
article
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article

Beyond the Metal: Sustained Efficacy and Diagnostic Nuances of Bioresorbable Coronary Scaffolds

Praneeth Polamuri, Anoop Agrawal
Indian Journal of Clinical Cardiology
Coronary Interventions and Diagnostics
article

Beyond the Metal: Sustained Efficacy and Diagnostic Nuances of Bioresorbable Coronary Scaffolds

Praneeth Polamuri, Anoop Agrawal
article en

Abstract

Bioresorbable vascular scaffolds offer temporary mechanical support and local drug delivery to coronary arteries, ultimately restoring native vessel physiology after resorption. This case describes a 62-year-old man who underwent percutaneous coronary intervention with a second-generation sirolimus-eluting MeRes100 scaffold for significant proximal left anterior descending artery stenosis. Four years post-implantation, the patient remained asymptomatic but presented with intermittent, atypical chest pain. Coronary computed tomography angiography revealed complete scaffold resorption and preserved vessel patency, though interpretation was complicated by blooming artefacts from residual metallic markers. Second-generation scaffolds like MeRes100 show improved mechanical properties, predictable bioresorption profiles, and excellent clinical outcomes, including low rates of thrombosis and restoration of vasomotion. This case highlights both the long-term safety and efficacy of MeRes100 and the limitations posed by imaging artefacts, emphasizing the need for cautious computed tomography interpretation after scaffold resorption.

Indian Journal of Clinical Cardiology
Yashoda Hospital (IN)
Good health and well-being
Openalex Percentile: Top 14%
Coronary Interventions and Diagnostics
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