Laser peripheral iridotomy for treating recurrent uveitis-glaucoma-hyphema plus syndrome with a scleral fixed intraocular lens: a case report

The purpose of this study was to provide a case report of a patient with uveitis-glaucoma-hyphema-vitreous hemorrhage (UGH plus) syndrome with intraocular lens (IOL) scleral fixation who presented with recurrent decreased vision and to discuss potential risk factors and treatment options. A 54-year-old man with a history of multiple ocular traumas and surgeries underwent IOL reposition surgery (scleral fixation) in his right eye in July 2020. He complained of having blurred vision after rubbing his right eye in February 2023. We diagnosed him with UGH plus syndrome on the basis of successive anterior chamber inflammation, elevated intraocular pressure (IOP), hyphema and vitreous hemorrhage. Ultrasound biomicroscopy revealed a concave iris. Laser peripheral iridotomy (LPI) effectively controls UGH plus syndrome. We reported the successful management of UGH plus syndrome with a scleral-fixed IOL via the LPI. Given the increasing prevalence of IOL implantation, great importance should be attached to the possibility of UGH syndrome, especially in patients with high-risk factors.

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Publication Details

Journal
BMC Ophthalmology
Published
2026-03-21
DOI
https://doi.org/10.1186/s12886-026-04720-0
Primary Topic
Intraocular Surgery and Lenses
Type
article
Field-Weighted Citation Impact
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article

Laser peripheral iridotomy for treating recurrent uveitis-glaucoma-hyphema plus syndrome with a scleral fixed intraocular lens: a case report

Ao Miao, J Chen, Peimin Lin, Fan Yang et al.
BMC Ophthalmology
Intraocular Surgery and Lenses
article

Laser peripheral iridotomy for treating recurrent uveitis-glaucoma-hyphema plus syndrome with a scleral fixed intraocular lens: a case report

Ao Miao, J Chen, Peimin Lin, Fan Yang, Tianyu Zheng, Jiayi Xu, Dongjin Qian
article en

Abstract

The purpose of this study was to provide a case report of a patient with uveitis-glaucoma-hyphema-vitreous hemorrhage (UGH plus) syndrome with intraocular lens (IOL) scleral fixation who presented with recurrent decreased vision and to discuss potential risk factors and treatment options. A 54-year-old man with a history of multiple ocular traumas and surgeries underwent IOL reposition surgery (scleral fixation) in his right eye in July 2020. He complained of having blurred vision after rubbing his right eye in February 2023. We diagnosed him with UGH plus syndrome on the basis of successive anterior chamber inflammation, elevated intraocular pressure (IOP), hyphema and vitreous hemorrhage. Ultrasound biomicroscopy revealed a concave iris. Laser peripheral iridotomy (LPI) effectively controls UGH plus syndrome. We reported the successful management of UGH plus syndrome with a scleral-fixed IOL via the LPI. Given the increasing prevalence of IOL implantation, great importance should be attached to the possibility of UGH syndrome, especially in patients with high-risk factors.

BMC Ophthalmology
Tongji University (CN), Shanghai Eye Disease Prevention & Treatment Center (CN), Eye & ENT Hospital of Fudan University (CN), Shanghai Tenth People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 13%
Intraocular Surgery and Lenses
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