The Arterial Deficit: Characterizing Erectile Dysfunction with Penile Colour Doppler in a Ugandan Population.

To evaluate the diagnostic utility of penile colour Doppler ultrasonography (CDU) in characterizing the vascular etiology of erectile dysfunction (ED) in a Ugandan population. A retrospective analysis was conducted on 51 patients with non-neurological, non-metabolic ED at a tertiary institution. All patients underwent standardized penile CDU after intracavernosal injection of 20 µg Prostaglandin E1 (PGE1), with assessment of peak systolic velocity (PSV), end-diastolic velocity (EDV), and cavernosal artery diameter. The mean age was 48.65 years. Arterial insufficiency was the most common finding (45.1% of cases), with 78.26% of these being bilateral. Mixed arterial-venous dysfunction was identified in 35.29% of patients, while isolated venous leakage was rare (3.92%). Only 13.73% of studies were normal. A key finding was the disparity between structural and functional assessments: while B-mode ultrasound appeared normal in 74.51% of cases, Doppler revealed vascular abnormalities in the vast majority. Penile CDU is a valuable non-invasive tool for detecting vasculogenic ED in this setting, with arterial insufficiency being the predominant etiology. The frequent discrepancy between normal B-mode anatomy and abnormal hemodynamics highlights the essential role of doppler velocimetry in diagnosis.

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Journal
African Journal of Urology
Published
2026-03-21
DOI
https://doi.org/10.1186/s12301-026-00558-6
Primary Topic
Sexual function and dysfunction studies
Type
article
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article

The Arterial Deficit: Characterizing Erectile Dysfunction with Penile Colour Doppler in a Ugandan Population.

Henry Sematimba, Frank Ssebaggala, Ampuriire Nyakubaho, Victoria Nakalanzi et al.
African Journal of Urology
Sexual function and dysfunction studies
article

The Arterial Deficit: Characterizing Erectile Dysfunction with Penile Colour Doppler in a Ugandan Population.

Henry Sematimba, Frank Ssebaggala, Ampuriire Nyakubaho, Victoria Nakalanzi, Michael Kawooya G, Melodie Munyakazi
article en

Abstract

To evaluate the diagnostic utility of penile colour Doppler ultrasonography (CDU) in characterizing the vascular etiology of erectile dysfunction (ED) in a Ugandan population. A retrospective analysis was conducted on 51 patients with non-neurological, non-metabolic ED at a tertiary institution. All patients underwent standardized penile CDU after intracavernosal injection of 20 µg Prostaglandin E1 (PGE1), with assessment of peak systolic velocity (PSV), end-diastolic velocity (EDV), and cavernosal artery diameter. The mean age was 48.65 years. Arterial insufficiency was the most common finding (45.1% of cases), with 78.26% of these being bilateral. Mixed arterial-venous dysfunction was identified in 35.29% of patients, while isolated venous leakage was rare (3.92%). Only 13.73% of studies were normal. A key finding was the disparity between structural and functional assessments: while B-mode ultrasound appeared normal in 74.51% of cases, Doppler revealed vascular abnormalities in the vast majority. Penile CDU is a valuable non-invasive tool for detecting vasculogenic ED in this setting, with arterial insufficiency being the predominant etiology. The frequent discrepancy between normal B-mode anatomy and abnormal hemodynamics highlights the essential role of doppler velocimetry in diagnosis.

African Journal of UrologyVol. 32(1)
Mengo Hospital (UG)
Good health and well-being
Openalex Percentile: Top 24%
Sexual function and dysfunction studies
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