Efficacy and safety of tirofiban combined with intravenous thrombolysis in Acute ischemic stroke: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials and observational studies

Tirofiban combined with IVT in AIS may improve recovery without significantly increasing bleeding or mortality. Further high-quality RCTs are needed to refine its use.

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Publication Details

Journal
Neurological Research
Published
2026-03-20
DOI
https://doi.org/10.1080/01616412.2026.2648166
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and safety of tirofiban combined with intravenous thrombolysis in Acute ischemic stroke: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials and observational studies

Taha Qazi, Bilal Khan, Mamur Khan, Akif Shahid Khan et al.
Neurological Research
Acute Ischemic Stroke Management
article

Efficacy and safety of tirofiban combined with intravenous thrombolysis in Acute ischemic stroke: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials and observational studies

Taha Qazi, Bilal Khan, Mamur Khan, Akif Shahid Khan, P. Dawer, Umer Zaryab Khan, Muhammad Huzaifa Khattak, Muhammad Shaheer, Sarah Idrees, Haris Wazir Khan
article en

Abstract

Tirofiban combined with IVT in AIS may improve recovery without significantly increasing bleeding or mortality. Further high-quality RCTs are needed to refine its use.

Neurological Research
Ayub Medical College (PK), Khyber Medical College (PK), Rawalpindi Medical University (PK), University College of Medical Sciences (IN), College of Medical Sciences (NP), The Northwest School (US)
Good health and well-being
Openalex Percentile: Top 16%
Acute Ischemic Stroke Management
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