Circulating cardiometabolic metabolite profiles associated with ambient air pollution and atrial fibrillation risk: a prospective cohort study

Air pollution-related metabolic signature was independently associated with AF risk and mediated a significant portion of pollution's arrhythmogenic effects. These findings provide novel insights into biological mechanisms linking environmental exposures to AF.

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Publication Details

Journal
Cardiovascular Diabetology
Published
2026-03-21
DOI
https://doi.org/10.1186/s12933-026-03129-9
Primary Topic
Air Quality and Health Impacts
Type
article
Field-Weighted Citation Impact
0.00
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Circulating cardiometabolic metabolite profiles associated with ambient air pollution and atrial fibrillation risk: a prospective cohort study

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Circulating cardiometabolic metabolite profiles associated with ambient air pollution and atrial fibrillation risk: a prospective cohort study

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article en

Abstract

Air pollution-related metabolic signature was independently associated with AF risk and mediated a significant portion of pollution's arrhythmogenic effects. These findings provide novel insights into biological mechanisms linking environmental exposures to AF.

Cardiovascular Diabetology
China Three Gorges University (CN), Yanbian University (CN), University of Milan (IT), University of Zurich (CH), University Hospitals of the Ruhr-University of Bochum (DE), United Nations University – Maastricht Economic and Social Research Institute on Innovation and Technology (NL), Southwest Medical University (CN), Maastricht University (NL), Wuhan University (CN), Universitätsklinik Marien Hospital Herne (DE), University Hospital of Zurich (CH), Hubei Provincial Center for Disease Control and Prevention (CN), Second Hospital of Yichang (CN), OLVG (NL), St. Josef-Hospital (DE), BG University Hospital Bergmannsheil Bochum (DE), Renmin Hospital of Wuhan University (CN), Ospedale Bassini (IT), University Medical Centre Mannheim (DE), Huazhong University of Science and Technology Hospital (CN), Huazhong University of Science and Technology (CN), Hubei University (CN), Ruhr University Bochum (DE)
Openalex Percentile: Top 15%
Air Quality and Health Impacts
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