Plasma exosome proteomics in different glucose statuses: a cross-sectional study on type 2 diabetes pathogenesis

The proteomic patterns of exosomes in groups with different glucose levels exhibited that even before overt diabetes manifests, the circulating exosome cargo signals immune and coagulatory activation distinct from normal physiology.

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Publication Details

Journal
Clinical Proteomics
Published
2026-03-21
DOI
https://doi.org/10.1186/s12014-026-09600-9
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Plasma exosome proteomics in different glucose statuses: a cross-sectional study on type 2 diabetes pathogenesis

Mingma Li, Haijian Guo, Yue Liu, Jinshui Xu et al.
Clinical Proteomics
Extracellular vesicles in disease
article

Plasma exosome proteomics in different glucose statuses: a cross-sectional study on type 2 diabetes pathogenesis

Mingma Li, Haijian Guo, Yue Liu, Jinshui Xu, Evan Yi-Wen Yu, Bei Wang, Yu Liu, Zilin Sun, Kaicheng Sun
article en

Abstract

The proteomic patterns of exosomes in groups with different glucose levels exhibited that even before overt diabetes manifests, the circulating exosome cargo signals immune and coagulatory activation distinct from normal physiology.

Clinical Proteomics
Chinese Center For Disease Control and Prevention (CN), Zhongda Hospital Southeast University (CN), Jiangsu Provincial Center for Disease Control and Prevention (CN), Yandex (Russia) (RU), Southeast University (CN)
Good health and well-being
Openalex Percentile: Top 14%
Extracellular vesicles in disease
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