Biological sex, but not obesity, independently predicts anatomical injury patterns in trauma bay patients: a multivariate retrospective analysis of 2,128 patients

Biological sex and kinetic energy are the primary determinants for severe overall and regional trauma. Conversely, obesity does not independently affect initial anatomical injury severity. The lack of independent impact from obesity suggests that sexual dimorphism in biomechanics, skeletal geometry, and tissue resilience - rather than absolute obesity - underlies the increased vulnerability of males in acute trauma.

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Publication Details

Journal
Biology of Sex Differences
Published
2026-03-21
DOI
https://doi.org/10.1186/s13293-026-00883-z
Primary Topic
Trauma and Emergency Care Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Biological sex, but not obesity, independently predicts anatomical injury patterns in trauma bay patients: a multivariate retrospective analysis of 2,128 patients

Felix Klingler, Benjamin Erdle, Nils Mühlenfeld, J. P. Maier et al.
Biology of Sex Differences
Trauma and Emergency Care Studies
article

Biological sex, but not obesity, independently predicts anatomical injury patterns in trauma bay patients: a multivariate retrospective analysis of 2,128 patients

Felix Klingler, Benjamin Erdle, Nils Mühlenfeld, J. P. Maier, C. Pietsch, H. Schmal, F. C. Wagner
article en

Abstract

Biological sex and kinetic energy are the primary determinants for severe overall and regional trauma. Conversely, obesity does not independently affect initial anatomical injury severity. The lack of independent impact from obesity suggests that sexual dimorphism in biomechanics, skeletal geometry, and tissue resilience - rather than absolute obesity - underlies the increased vulnerability of males in acute trauma.

Biology of Sex Differences
University of Freiburg (DE), University Medical Center Freiburg (DE), Odense University Hospital (DK)
Openalex Percentile: Top 18%
Trauma and Emergency Care Studies
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