Mahuang decoction targets fluid retention in heart failure with preserved ejection fraction
MHD ameliorated HFpEF through dual mechanisms involving p38 MAPK/AQPs regulation and PCSK6/Corin/ANP signaling, providing a promising approach for targeting the fluid retention in HFpEF therapy.
Authors
- Yongcheng Liu (ORCID: https://orcid.org/0000-0001-9289-7131)
- Guoju Dong (ORCID: https://orcid.org/0000-0003-4100-4465)
- Yuanchang Zhang
- Luqi Huang
- Ziyi Chen
- Xiaoyu Liang
- Yue Wei
- Siyu Liu
- Xiaopeng Hao
- Yinong Liu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Xiyuan Hospital (CN)
- China Academy of Chinese Medical Sciences (CN)
Publication Details
- Journal
- Phytomedicine
- Published
- 2026-03-21
- DOI
- https://doi.org/10.1016/j.phymed.2026.158099
- Primary Topic
- Hemodynamic Monitoring and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00