Clomiphene citrate in the management of anovulation: a review of mechanisms, outcomes, and clinical challenges

While CC remains a cornerstone for inducing ovulation, its peripheral anti-estrogenic effects and significant rate of resistance necessitate adjunctive strategies, careful patient selection, and a transition to advanced therapies when needed to improve live birth outcomes.

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Publication Details

Journal
Gynecological Endocrinology
Published
2026-03-21
DOI
https://doi.org/10.1080/09513590.2026.2646774
Primary Topic
Ovarian function and disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Clomiphene citrate in the management of anovulation: a review of mechanisms, outcomes, and clinical challenges

Telila Mesfin Tadesse
Gynecological Endocrinology
Ovarian function and disorders
article

Clomiphene citrate in the management of anovulation: a review of mechanisms, outcomes, and clinical challenges

Telila Mesfin Tadesse
article en

Abstract

While CC remains a cornerstone for inducing ovulation, its peripheral anti-estrogenic effects and significant rate of resistance necessitate adjunctive strategies, careful patient selection, and a transition to advanced therapies when needed to improve live birth outcomes.

Gynecological EndocrinologyVol. 42(1)
Madda Walabu University (ET)
Zero hunger, Good health and well-being
Openalex Percentile: Top 11%
Ovarian function and disorders
DOIOpen Access PDFOpenAlex
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