Integrated bioinformatics analysis reveals cross-talking hub genes and therapeutic agents between sepsis and acute myocardial infarction
<i>JAK2, MYD88</i>, and <i>TIMP1</i> were identified as shared core genes in sepsis and AMI. These genes not only serve as potential diagnostic biomarkers but also offer novel targets for developing common therapeutic strategies for both conditions. Furthermore, quercetin emerges as a promising candidate for targeted treatment.
Authors
- Maolin Chen (ORCID: https://orcid.org/0000-0002-0806-4223)
- Wenhao Chen (ORCID: https://orcid.org/0000-0002-0626-3739)
- Lihuimei Zhou
- Jiafu Li
Institutions
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2026-03-21
- DOI
- https://doi.org/10.1080/07853890.2026.2645276
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 0.00