The Cost Utility of Rhythm Control Treatment Sequences in Patients with Atrial Fibrillation: Anti-arrhythmic Drugs Versus Catheter Ablation
Our model suggests that rhythm control with at least one CA is cost effective compared with only AADs in patients with atrial fibrillation requiring rhythm control. Within shared decision making, first-line CA, followed by AADs to manage atrial fibrillation recurrences, with a maximum of three repeat ablations, represents the most cost-effective strategy for patients with symptomatic atrial fibrillation requiring rhythm control.
Authors
- Simone Huygens (ORCID: https://orcid.org/0000-0003-0669-4149)
- Sing-Chien Yap
- Matthijs Versteegh (ORCID: https://orcid.org/0000-0003-4804-235X)
- Michiel Rienstra
- Dominik Linz
- Martin Hemels
Institutions
- University Medical Center Groningen (NL)
- Radboud University Nijmegen (NL)
- Erasmus MC (NL)
- Radboud University Medical Center (NL)
- Maastricht University (NL)
- National Health Care Institute (NL)
- Rijnstate Hospital (NL)
Publication Details
- Journal
- PharmacoEconomics
- Published
- 2026-03-21
- DOI
- https://doi.org/10.1007/s40273-026-01604-5
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00