HC-HA/PTX3 from amniotic membrane reprograms human corneal fibroblasts to neural crest progenitors by switching from canonical to noncanonical TGFβ signaling
Thus, HC-HA/PTX3 from amniotic membrane can be deployed as a new strategy to reverse scar toward regeneration.
Authors
- Yuan Zhang (ORCID: https://orcid.org/0000-0001-5784-4421)
- Yi Zhu (ORCID: https://orcid.org/0000-0002-1778-8880)
- Scheffer C.G. Tseng
- Sean Tighe
- Allison Helman
Institutions
- University of Miami (US)
- BioSurfaces (United States) (US)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2026-03-21
- DOI
- https://doi.org/10.1186/s13287-026-04983-w
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00