Targeting the gut microbiota as treatment for obesity and cancer cachexia
The gut microbiota holds potential as a therapeutic target in metabolic diseases, offering opportunities for precision medicine based on microbial and metabolic profiles. While early microbiota-based therapies show promise, further investigation into mechanistic pathways and novel engineered microbiota is essential to develop effective treatments for obesity and cachexia.
Authors
- Tom van den Ende (ORCID: https://orcid.org/0000-0003-2830-2310)
- Hanneke W.M. van Laarhoven (ORCID: https://orcid.org/0000-0003-1274-5643)
- Nicolien C. de Clercq (ORCID: https://orcid.org/0000-0002-9924-7171)
- Anna Giannakogeorgou (ORCID: https://orcid.org/0009-0009-7817-803X)
- Max Nieuwdorp
- Barbara J.H. Verhaar
Institutions
- Amsterdam University Medical Centers (NL)
- Cancer Center Amsterdam (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Expert Opinion on Emerging Drugs
- Published
- 2026-03-21
- DOI
- https://doi.org/10.1080/14728214.2026.2650180
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00