An analysis of clinical manifestations and therapeutic outcomes in pediatric connective tissue disease-associated interstitial lung disease

Pediatric CTD-ILD often has an insidious onset with non-specific respiratory symptoms. Chest HRCT and pulmonary function testing are important tools for early evaluation and detection. In our cohort, treatment with corticosteroids and immunosuppressants was associated with improvements in lung function and imaging findings, supporting the potential benefit of early recognition and timely management.

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Publication Details

Journal
Pediatric Rheumatology
Published
2026-03-21
DOI
https://doi.org/10.1186/s12969-026-01208-5
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
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article

An analysis of clinical manifestations and therapeutic outcomes in pediatric connective tissue disease-associated interstitial lung disease

Qing Peng, Tingting Yuan, Na Chen, Shan Qiu et al.
Pediatric Rheumatology
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

An analysis of clinical manifestations and therapeutic outcomes in pediatric connective tissue disease-associated interstitial lung disease

Qing Peng, Tingting Yuan, Na Chen, Shan Qiu, Qiancheng Li, Zhaowen Zhong
article en

Abstract

Pediatric CTD-ILD often has an insidious onset with non-specific respiratory symptoms. Chest HRCT and pulmonary function testing are important tools for early evaluation and detection. In our cohort, treatment with corticosteroids and immunosuppressants was associated with improvements in lung function and imaging findings, supporting the potential benefit of early recognition and timely management.

Pediatric Rheumatology
Xuzhou Medical College (CN), Xuzhou Children Hospital (CN)
Good health and well-being
Openalex Percentile: Top 15%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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An analysis of clinical manifestations and therapeutic outcomes in pediatric connective tissue disease-associated interstitial lung disease — Qing Peng, Tingting Yuan, et al. · Pediatric Rheumatology (2026) | TGRS Research Map | TGRS