<i>Portulaca oleracea</i> L. extract improves wound healing and is associated with VEGF-related marker activation in a rat model of infected dorsal full-thickness skin wound
In a rat model of fecal-contaminated dorsal skin wound infection, topical POL treatment was associated with improved histological outcomes, reduced inflammation, and increased VEGF-related markers. These findings suggest a potential role for POL in promoting infected wound healing, although the VEGF involvement is based on associative expression data and requires further mechanistic validation.
Authors
- Chenyang Fang (ORCID: https://orcid.org/0000-0002-0752-8700)
- Yanni Pei
- Yin Qu (ORCID: https://orcid.org/0000-0002-3428-4289)
- Wen Zhang (ORCID: https://orcid.org/0000-0001-5166-0736)
- W. Yang
- Yafeng Lu
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Shuguang Hospital (CN)
Publication Details
- Journal
- Cutaneous and Ocular Toxicology
- Published
- 2026-03-21
- DOI
- https://doi.org/10.1080/15569527.2026.2645827
- Primary Topic
- Antioxidants, Aging, Portulaca oleracea
- Type
- article
- Field-Weighted Citation Impact
- 0.00