Sex differences in the incidence of composite ischemic and bleeding events in ischemic stroke patients with nonvalvular atrial fibrillation and atherosclerosis

In this post hoc analysis of the ATIS-NVAF trial, no significant sex differences were observed in the 2-year composite of cardiovascular and bleeding events among patients with recent ischemic stroke or TIA and concomitant NVAF and ASCVD. Appropriate medical management may attenuate the influence of biological sex on the risk of cardiovascular and bleeding events.

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Publication Details

Journal
Journal of Stroke and Cerebrovascular Diseases
Published
2026-03-21
DOI
https://doi.org/10.1016/j.jstrokecerebrovasdis.2026.108615
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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Sex differences in the incidence of composite ischemic and bleeding events in ischemic stroke patients with nonvalvular atrial fibrillation and atherosclerosis

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Sex differences in the incidence of composite ischemic and bleeding events in ischemic stroke patients with nonvalvular atrial fibrillation and atherosclerosis

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article en

Abstract

In this post hoc analysis of the ATIS-NVAF trial, no significant sex differences were observed in the 2-year composite of cardiovascular and bleeding events among patients with recent ischemic stroke or TIA and concomitant NVAF and ASCVD. Appropriate medical management may attenuate the influence of biological sex on the risk of cardiovascular and bleeding events.

Journal of Stroke and Cerebrovascular DiseasesVol. 35(5)
Hyogo Medical University (JP), Kyorin University (JP), Osaka National Hospital (JP), Iwate Prefectural Central Hospital (JP), National Cerebral and Cardiovascular Center (JP), University of Tsukuba Hospital (JP), Kohnan Hospital (JP), Hyogo Prefectural Nishinomiya Hospital (JP), Osaka University Hospital (JP), Kobe City Medical Center General Hospital (JP), Hyogo University (JP), Kobe College (JP)
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Atrial Fibrillation Management and Outcomes
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