Thermal adaptation crosstalk with azole response through lncRNA in <i>Aspergillus fumigatus</i>

<i>Aspergillus fumigatus</i> is the causative agent of most mold associated infections and can tolerate temperatures above 50°C. A lncRNA levels negatively correlate with increasing temperature, and this increases the fungi's ability to tolerate azole drugs both <i>in vitro</i> and <i>in vivo</i> . Changing the levels of <i>afu-182</i> improves anti-fungal treatment outcomes.