Squamous Cell Carcinoma in a Burn Scar Presenting as a Necrotizing Soft Tissue Infection: A Case Report

Marjolin’s ulcer (MU), the most frequently encountered form of squamous cell carcinoma arising in burn scars, may manifest either acutely - within the first year post-injury - or as a chronic condition, sometimes developing decades later. It is estimated that Marjolin's ulcers represent a small percentage of all cutaneous squamous cell carcinomas originating in non-grafted burn scars that have healed by secondary intention. The early surgical grafting of burn wounds has been suggested as a potential preventive measure against malignant transformation. Marjolin’s ulcers are characteristically aggressive, often associated with poor clinical outcomes and very high recurrence rates. We highlight a presentation mimicking necrotizing soft tissue infection in a previously grafted burn scar.