Practical Approach to Hormone Replacement Therapy for (Peri) Menopausal Women With Schizophrenia Spectrum Disorders: A Case Series

Hormone replacement therapy appears feasible and acceptable for women with SSD before and after the menopausal transition, with potential benefits for mood and functional improvement and high tolerability. Individualized approaches and safety considerations are essential. This approach may be integrated into routine psychiatric care, though larger studies with standardized outcomes are needed.