Salvage Metastasectomy After Adoptive Cell Transfer for Melanoma: Long-Term Updates
Of patients experiencing oligoprogression after initial response to ACT (complete response, partial response, or SD6), 27% derived durable disease control after surgical management, confirming a potentially viable salvage option for "local" failures following ACT that may not portend systemic failure. Additional factors related to ACT response and oligoprogression that may guide patient selection for salvage metastasectomy remain undefined.
Authors
- Nicholas D. Klemen (ORCID: https://orcid.org/0000-0003-1353-539X)
- David S. Schrump (ORCID: https://orcid.org/0000-0003-3613-1400)
- Kyle Hitscherich (ORCID: https://orcid.org/0000-0001-8081-356X)
- Stephanie L. Goff (ORCID: https://orcid.org/0000-0003-3317-9804)
- Sanjeev Krishna (ORCID: https://orcid.org/0000-0003-0066-0634)
- Jonathan M. Hernandez
- Alexandra Gustafson
- James C. Yang
- Steven A. Rosenberg
- Chuong D. Hoang
- Aaron J. Dinerman
- Donald E. White
- Paul F. Robbins
- Mei Li Kwong
- Jared J. Gartner
Institutions
- National Institutes of Health (US)
- National Cancer Institute (US)
Publication Details
- Journal
- Annals of Surgical Oncology
- Published
- 2026-03-21
- DOI
- https://doi.org/10.1245/s10434-026-19354-1
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00