Inhaled Nitric Oxide for Acute Right Heart Failure in Pulmonary Hypertension ― Bridging the Evidence-to-Practice Gap ―

including inotropes, vasopressors, and oxygen administration, is being used to optimize preload, afterload, and cardiac contractility (Figure ). 1,5However, there is a lack of high-quality evidence regarding pharmacological strategy during the acute phase for pulmonary vasodilators D ecompensated acute right heart failure (RHF) is one of the most severe complications pulmonary hypertension (PH). 1 Despite recent progress in disease-specific treatment, such as selective pulmonary vasodilators and balloon pulmonary angioplasty, 2-4 patients with acute RHF due to PH have high morbidity and mortality rates.Most of these patients require intensive care, but therapeutic options remain limited.Supportive therapy,

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Publication Details

Journal
Circulation Journal
Published
2026-03-20
DOI
https://doi.org/10.1253/circj.cj-26-0253
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
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article

Inhaled Nitric Oxide for Acute Right Heart Failure in Pulmonary Hypertension ― Bridging the Evidence-to-Practice Gap ―

Shunsuke Tatebe, S Y Yasuda
Circulation Journal
Pulmonary Hypertension Research and Treatments
article

Inhaled Nitric Oxide for Acute Right Heart Failure in Pulmonary Hypertension ― Bridging the Evidence-to-Practice Gap ―

Shunsuke Tatebe, S Y Yasuda
article en

Abstract

including inotropes, vasopressors, and oxygen administration, is being used to optimize preload, afterload, and cardiac contractility (Figure ). 1,5However, there is a lack of high-quality evidence regarding pharmacological strategy during the acute phase for pulmonary vasodilators D ecompensated acute right heart failure (RHF) is one of the most severe complications pulmonary hypertension (PH). 1 Despite recent progress in disease-specific treatment, such as selective pulmonary vasodilators and balloon pulmonary angioplasty, 2-4 patients with acute RHF due to PH have high morbidity and mortality rates.Most of these patients require intensive care, but therapeutic options remain limited.Supportive therapy,

Circulation Journal
Tohoku Institute of Technology (JP), Tohoku University (JP)
Good health and well-being
Openalex Percentile: Top 15%
Pulmonary Hypertension Research and Treatments
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