Utility of 18F-FDG PET/CT in the Surveillance of Patients With Neurofibromatosis Type 1

In this cohort of 79 adult patients with NF1, <sup>18</sup>F-FDG PET/CT proved as a valuable complementary imaging modality to conventional imaging by enabling the detection of incidental malignant or potentially malignant tumors. Our results highlight <sup>18</sup>F-FDG PET/CT's beneficial impact on disease management by suggesting that the incorporation of <sup>18</sup>F-FDG PET/CT into screening protocols could improve early detection of NF1-related cancers in asymptomatic adults, potentially offering early treatment options to improve clinical outcomes.

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Publication Details

Journal
Neurology Genetics
Published
2026-03-20
DOI
https://doi.org/10.1212/nxg.0000000000200361
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
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article

Utility of 18F-FDG PET/CT in the Surveillance of Patients With Neurofibromatosis Type 1

Mathieu Blais, François-Alexandre Buteau, Rahma Derbel, Hélène T. Khuong et al.
Neurology Genetics
Neurofibromatosis and Schwannoma Cases
article

Utility of 18F-FDG PET/CT in the Surveillance of Patients With Neurofibromatosis Type 1

Mathieu Blais, François-Alexandre Buteau, Rahma Derbel, Hélène T. Khuong, Vincent Roy, Manon Leclerc, R Lamontagne, Lina Djilani, Mathilde Baril, François Gros-Louis, Nicolas Dupre, Maria Gabriela Tanase
article en

Abstract

In this cohort of 79 adult patients with NF1, <sup>18</sup>F-FDG PET/CT proved as a valuable complementary imaging modality to conventional imaging by enabling the detection of incidental malignant or potentially malignant tumors. Our results highlight <sup>18</sup>F-FDG PET/CT's beneficial impact on disease management by suggesting that the incorporation of <sup>18</sup>F-FDG PET/CT into screening protocols could improve early detection of NF1-related cancers in asymptomatic adults, potentially offering early treatment options to improve clinical outcomes.

Neurology GeneticsVol. 12(2)
Centre hospitalier de l'Université Laval (CA), Université Laval (CA)
Good health and well-being
Openalex Percentile: Top 22%
Neurofibromatosis and Schwannoma Cases
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