Cost-Effectiveness of Oral Immunotherapy Treatments vs No Treatment for Peanut Allergy in Children

This economic evaluation found that for remission, both PPOIT and OIT were cost-effective and good value compared with no treatment, with OIT associated with a larger effect size but no clinically meaningful difference. When QALYs are prioritized, PPOIT offers the best value. Key factors associated with cost-effectiveness were treatment product pricing and patient quality of life.

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Publication Details

Journal
JAMA Network Open
Published
2026-03-20
DOI
https://doi.org/10.1001/jamanetworkopen.2026.2410
Primary Topic
Food Allergy and Anaphylaxis Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Cost-Effectiveness of Oral Immunotherapy Treatments vs No Treatment for Peanut Allergy in Children

Melanie Lloyd, Paxton Loke, Kim Dalziel, P. Quinn et al.
JAMA Network Open
Food Allergy and Anaphylaxis Research
article

Cost-Effectiveness of Oral Immunotherapy Treatments vs No Treatment for Peanut Allergy in Children

Melanie Lloyd, Paxton Loke, Kim Dalziel, P. Quinn, Mimi L. K. Tang, Li Huang, Michael Gold, Adam Franz, Michael O’Sullivan
article en

Abstract

This economic evaluation found that for remission, both PPOIT and OIT were cost-effective and good value compared with no treatment, with OIT associated with a larger effect size but no clinically meaningful difference. When QALYs are prioritized, PPOIT offers the best value. Key factors associated with cost-effectiveness were treatment product pricing and patient quality of life.

JAMA Network OpenVol. 9(3)
Royal Children's Hospital (AU), The University of Melbourne (AU), University of South Australia (AU), The Kids Research Institute Australia (AU), The University of Western Australia (AU), Princess Margaret Hospital for Children (AU), Women's and Children's Hospital (AU), Monash Health (AU), Murdoch Children's Research Institute (AU), Melbourne Health (AU), The University of Adelaide (AU), Victoria University (AU)
Zero hunger
Openalex Percentile: Top 12%
Food Allergy and Anaphylaxis Research
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