A Review of Pituitary Duplication and First Report of Associated Precocious Puberty in a Boy

This is the first reported case of CPP in a male with pituitary duplication. The findings highlight the need for awareness of endocrine dysfunction, including CPP, in patients with pituitary malformations. The gender disparity of CPP in pituitary duplication remains unexplained, and further research into genetic and molecular mechanisms, notably Sonic Hedgehog signaling, is required to understand this association.

Authors

Publication Details

Journal
Hormone Research in Paediatrics
Published
2026-03-20
DOI
https://doi.org/10.1159/000551549
Primary Topic
Teratomas and Epidermoid Cysts
Type
article
Field-Weighted Citation Impact
0.00
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article

A Review of Pituitary Duplication and First Report of Associated Precocious Puberty in a Boy

Karine Aouchiche, Mirjam Dirlewanger, Sarah Castets, Mehul Dattani et al.
Hormone Research in Paediatrics
Teratomas and Epidermoid Cysts
article

A Review of Pituitary Duplication and First Report of Associated Precocious Puberty in a Boy

Karine Aouchiche, Mirjam Dirlewanger, Sarah Castets, Mehul Dattani, Valerie Schwitzgebel
article en

Abstract

This is the first reported case of CPP in a male with pituitary duplication. The findings highlight the need for awareness of endocrine dysfunction, including CPP, in patients with pituitary malformations. The gender disparity of CPP in pituitary duplication remains unexplained, and further research into genetic and molecular mechanisms, notably Sonic Hedgehog signaling, is required to understand this association.

Hormone Research in Paediatrics
Gender equality
Openalex Percentile: Top 14%
Teratomas and Epidermoid Cysts
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