A Review of Pituitary Duplication and First Report of Associated Precocious Puberty in a Boy
This is the first reported case of CPP in a male with pituitary duplication. The findings highlight the need for awareness of endocrine dysfunction, including CPP, in patients with pituitary malformations. The gender disparity of CPP in pituitary duplication remains unexplained, and further research into genetic and molecular mechanisms, notably Sonic Hedgehog signaling, is required to understand this association.
Authors
- Karine Aouchiche (ORCID: https://orcid.org/0009-0008-5550-9636)
- Mirjam Dirlewanger
- Sarah Castets
- Mehul Dattani
- Valerie Schwitzgebel
Publication Details
- Journal
- Hormone Research in Paediatrics
- Published
- 2026-03-20
- DOI
- https://doi.org/10.1159/000551549
- Primary Topic
- Teratomas and Epidermoid Cysts
- Type
- article
- Field-Weighted Citation Impact
- 0.00