Perceptions of Prognosis and Hope Among Patients With Advanced Cancer at the Time of Enrollment in an Early-Phase Clinical Trial

At the time of enrollment in an EPCT, we found no association between patients' hope and perception of the intent of cancer therapy or report of having discussed their prognosis with their oncologist. These findings suggest that patients can have hope despite acknowledging the noncurative intent of their therapy and prognostic discussions.

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Publication Details

Journal
JCO Oncology Practice
Published
2026-03-20
DOI
https://doi.org/10.1200/op-25-01121
Primary Topic
Optimism, Hope, and Well-being
Type
article
Field-Weighted Citation Impact
0.00
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article

Perceptions of Prognosis and Hope Among Patients With Advanced Cancer at the Time of Enrollment in an Early-Phase Clinical Trial

Ryan David Nipp, Andrea Pelletier, Jennifer S. Temel, Laura A. Petrillo et al.
JCO Oncology Practice
Optimism, Hope, and Well-being
article

Perceptions of Prognosis and Hope Among Patients With Advanced Cancer at the Time of Enrollment in an Early-Phase Clinical Trial

Ryan David Nipp, Andrea Pelletier, Jennifer S. Temel, Laura A. Petrillo, Debra Lundquist, Cynthia Moore, Leah L. Thompson, M. Boulanger, Sienna Durbin, Anh B. Lam, Viola Bame, Rachel B. Jimenez, Dejan Juric
article en

Abstract

At the time of enrollment in an EPCT, we found no association between patients' hope and perception of the intent of cancer therapy or report of having discussed their prognosis with their oncologist. These findings suggest that patients can have hope despite acknowledging the noncurative intent of their therapy and prognostic discussions.

JCO Oncology Practice
Brigham and Women's Hospital (US), Massachusetts General Hospital (US), Office of Patient Care Services (US), Oklahoma State University Oklahoma City (US), University of Oklahoma Health Sciences Center (US), University of Oklahoma (US)
Openalex Percentile: Top 15%
Optimism, Hope, and Well-being
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