What is the significance of a new breast mass in women aged 40 or above? A cross-sectional study
While our institutional protocol increased the sensitivity and could lead to early detection, it lowered specificity, suggesting more false positive results. Our main suggestion is to consider "recency of a solid mass" as a criterion for suspiciousness in BI-RADS assignment to breast masses. We propose further studies to achieve a protocol that maximizes both sensitivity and specificity without compromising diagnostic reliability, and to find the cut-off for age when the effect of this factor increases.
Authors
- Amirhossein Eskandari (ORCID: https://orcid.org/0000-0001-7988-3050)
- Mandana Motamedi
- Azin Saberi (ORCID: https://orcid.org/0000-0002-2761-2045)
- Sadaf Alipour
- Kasra Jafari
Institutions
- Ministry of Health and Medical Education (IR)
- Motamed Cancer Institute (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-03-20
- DOI
- https://doi.org/10.1371/journal.pone.0341732
- Primary Topic
- Breast Lesions and Carcinomas
- Type
- article
- Field-Weighted Citation Impact
- 0.00