Application of chromosomal microarray analysis for fetuses with nasal bone agenesis or hypoplasia
Fetal nasal bone agenesis or hypoplasia is associated with chromosomal disorders. Notably, non-isolated nasal defects increase the risk of chromosomal alterations. Combined with CMA analysis, alterations caused by microdeletions or microinsertions can be detected. This approach can be used for clinical antenatal evaluation.
Authors
- Xiayuan Xu
- Keqin Jin (ORCID: https://orcid.org/0000-0003-4309-4791)
- Shuangshuang Shen (ORCID: https://orcid.org/0009-0004-9063-0184)
- Yanfen Yang
- Min Hu
- Jianfeng Luo
- Yue Qian
- Na Li
- Jun Zhang
Institutions
- Jingzhou Maternal and Child Health Hospital (CN)
- Jinhua Academy of Agricultural Sciences (CN)
- Guang Fu Hospital (CN)
- Jinhua Central Hospital (CN)
Publication Details
- Journal
- Molecular Cytogenetics
- Published
- 2026-03-20
- DOI
- https://doi.org/10.1186/s13039-026-00757-4
- Primary Topic
- Congenital Ear and Nasal Anomalies
- Type
- article
- Field-Weighted Citation Impact
- 0.00