Renal cell carcinoma presenting with orbital metastasis as the initial symptom: A case report

This case highlights the importance of considering metastatic disease in the differential diagnosis of orbital masses, even in the absence of systemic symptoms. The rarity of orbital metastasis from RCC suggests possible organ-specific metastatic pathways and underscores the need for further investigation into tumor heterogeneity and the molecular mechanisms of site-specific metastasis. Awareness of the diagnostic and management strategies for orbital metastases is clinically important.

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Publication Details

Journal
Medicine
Published
2026-03-20
DOI
https://doi.org/10.1097/md.0000000000048092
Primary Topic
Ocular Oncology and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Renal cell carcinoma presenting with orbital metastasis as the initial symptom: A case report

C H Liu, Sunan Shi, Xuexia Wang, Wenxin Dong et al.
Medicine
Ocular Oncology and Treatments
article

Renal cell carcinoma presenting with orbital metastasis as the initial symptom: A case report

C H Liu, Sunan Shi, Xuexia Wang, Wenxin Dong, Ranran Liu, Zhenhua Qiao, Zhitao Fan
article en

Abstract

This case highlights the importance of considering metastatic disease in the differential diagnosis of orbital masses, even in the absence of systemic symptoms. The rarity of orbital metastasis from RCC suggests possible organ-specific metastatic pathways and underscores the need for further investigation into tumor heterogeneity and the molecular mechanisms of site-specific metastasis. Awareness of the diagnostic and management strategies for orbital metastases is clinically important.

MedicineVol. 105(12)
Hebei Eye Hospital (CN)
Good health and well-being
Openalex Percentile: Top 13%
Ocular Oncology and Treatments
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