Interlaboratory variability in laboratory testing and reporting of myositis autoantibodies
We have shown there is considerable variation in how myositis antibody testing is undertaken and the results obtained for key autoantibody specificities, which may impact on clinical decision-making. Dialogue between manufacturers, diagnostic laboratories and clinicians remains crucial and steps towards harmonisation between laboratories is urgently needed.
Authors
- Ross S. Sadler
- Benoît Nespola (ORCID: https://orcid.org/0000-0003-0618-6646)
- Susan H. O'Loughlin
- Helena Storfors
- Anna Brusch
- Laura Viñas-Giménez (ORCID: https://orcid.org/0000-0003-2913-1154)
- May Y. Choi (ORCID: https://orcid.org/0000-0003-3760-2737)
- Charmaine Donald
- Adrian Heaps
- Maria Teresa Sanz-Martínez (ORCID: https://orcid.org/0000-0001-5814-8698)
- I Půtová (ORCID: https://orcid.org/0000-0002-2724-9223)
- Paul Sciore
- Hector Chinoy (ORCID: https://orcid.org/0000-0001-6492-1288)
- Marie Mayrhofer
- Jiří Vencovský (ORCID: https://orcid.org/0000-0002-0851-0713)
- Sarah Tansley (ORCID: https://orcid.org/0000-0003-4633-9598)
- Yves Troyanov
- Chris Bundell
- Birthe Michiels (ORCID: https://orcid.org/0000-0002-3977-4172)
- Fionnuala McMorrow
- Neil J. McHugh
- Idil Ashur
- Georgina R. Harvey
- Martin Bluethner
- Ernesto Trallero-Araguás
- Masataka Kuwana
- Xavier Bossuyt
- Albert Selva-O’Callaghan
- Hui Lu
- Claire Coeshott
- Marie Hudson
- Océane Landon-Cardinal
- Juliet Dunphy
- Akira Yoshida
- Marvin J. Fritzler
- Jade Tyson
- Alain Meyer
- Johan Rönnelid
Institutions
- Uppsala University (SE)
- Royal National Hospital for Rheumatic Diseases (GB)
- North Bristol NHS Trust (GB)
- Uppsala University Hospital (SE)
- University of Calgary (CA)
- Charles University (CZ)
- Salford Royal NHS Foundation Trust (GB)
- Churchill Hospital (GB)
- Manchester Royal Infirmary (GB)
- National Jewish Health (US)
- Institute of Rheumatology (CZ)
- Salford Royal Hospital (GB)
- Medizinisches Versorgungszentrum Prof. Mathey, Prof. Schofer (DE)
- Vall d'Hebron Hospital Universitari (ES)
- Centre Hospitalier de l’Université de Montréal (CA)
- Royal United Hospital Bath NHS Trust (GB)
- Pathwest Laboratory Medicine (AU)
- Hôpital Civil, Strasbourg (FR)
- McGill University (CA)
- University of Bath (GB)
- Université de Strasbourg (FR)
- Nippon Medical School (JP)
- University of Colorado Denver (US)
- KU Leuven (BE)
Publication Details
- Journal
- Journal of Autoimmunity
- Published
- 2026-03-20
- DOI
- https://doi.org/10.1016/j.jaut.2026.103548
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 0.00