Tuberculosis in advanced chronic kidney disease: An Observational Study at a Tertiary Care Center in Mexico
In this Mexican small cohort, ACKD didn't significantly worsen TB outcomes compared with non-ACKD patients. An local pragmatic alternating regimen was used without apparent harm. These preliminary findings are limited by small sample size, limited statistical power, and lack of pharmacokinetic validation. Larger studies with drug monitoring are needed to optimize treatment for this vulnerable group.
Authors
- Héctor Rivera-Villegas (ORCID: https://orcid.org/0009-0009-9735-3892)
- JOSE SIFUENTES-OSORNIO
- Fernanda González-Lara
- Tomas Rafael Mercado-Torres
- Adriana del C Roblero-Abadía
- Jose Arturo Hernández-Ibarra (ORCID: https://orcid.org/0000-0001-9331-5877)
- Sandra Rajme-Lopez
- Alfredo Ponce de-León
- Zohar Guy
- A. Martínez-Guerra
- Karla M. Tamez-Torres
- Carla M. Román-Montes
- José Raúl Ruiz-Ruiz
Institutions
- Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (MX)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-03-20
- DOI
- https://doi.org/10.1371/journal.pone.0338570
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00