Conceptual design of growth-adaptive calcium phosphate cement implants for large paediatric cranial defects

The presented approach demonstrates the technical feasibility of a modular, growth-adaptive CPC-based cranial implant and establishes a validated design and manufacturing framework. This work provides a fundamental basis for future biomechanical, biological, and clinical investigations aimed at advancing growth-adaptive implants for paediatric cranial reconstruction.

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Publication Details

Journal
Biofabrication
Published
2026-03-20
DOI
https://doi.org/10.1088/1758-5090/ae5572
Primary Topic
Head and Neck Surgical Oncology
Type
article
Field-Weighted Citation Impact
0.00
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article

Conceptual design of growth-adaptive calcium phosphate cement implants for large paediatric cranial defects

Martin Pendzik, Stefan Holtzhausen, Holger Wilhelm Rudolf Schmidt, Sascha Heinemann et al.
Biofabrication
Head and Neck Surgical Oncology
article

Conceptual design of growth-adaptive calcium phosphate cement implants for large paediatric cranial defects

Martin Pendzik, Stefan Holtzhausen, Holger Wilhelm Rudolf Schmidt, Sascha Heinemann, Philipp Sembdner, Kristin Paetzold-Byhain
article en

Abstract

The presented approach demonstrates the technical feasibility of a modular, growth-adaptive CPC-based cranial implant and establishes a validated design and manufacturing framework. This work provides a fundamental basis for future biomechanical, biological, and clinical investigations aimed at advancing growth-adaptive implants for paediatric cranial reconstruction.

Biofabrication
Förderverein Institut für Medizintechnik Dresden (DE), Technische Universität Dresden (DE)
Openalex Percentile: Top 15%
Head and Neck Surgical Oncology
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