Rectal douching is associated with gut dysbiosis and metabolic disruption in HIV-uninfected men who have sex with men

Rectal douching among HIV-uninfected MSM is associated with gut microbiota dysbiosis, significant alterations in microbial metabolic profiles, and reduced gut barrier integrity. These findings underscore the need for increased awareness and health education within this population.

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Publication Details

Journal
Communications Medicine
Published
2026-03-20
DOI
https://doi.org/10.1038/s43856-026-01490-0
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Rectal douching is associated with gut dysbiosis and metabolic disruption in HIV-uninfected men who have sex with men

Anping Feng, Fenqi Da, Linghua Li, Dan Luo et al.
Communications Medicine
HIV-related health complications and treatments
article

Rectal douching is associated with gut dysbiosis and metabolic disruption in HIV-uninfected men who have sex with men

Anping Feng, Fenqi Da, Linghua Li, Dan Luo, Heping Zhao, Huachun Zou
article en

Abstract

Rectal douching among HIV-uninfected MSM is associated with gut microbiota dysbiosis, significant alterations in microbial metabolic profiles, and reduced gut barrier integrity. These findings underscore the need for increased awareness and health education within this population.

Communications Medicine
Sun Yat-sen University (CN), Fudan University (CN), Southwest Medical University (CN), Melbourne Sexual Health Centre (AU), Shanghai Public Health Clinical Center (CN), Guangzhou Eighth People's Hospital (CN), Guangzhou Medical University (CN)
Openalex Percentile: Top 18%
HIV-related health complications and treatments
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