<i>Klebsiella</i> Enrichment Is Associated with Disease Severity in Ulcerative Colitis

UC demonstrates gut dysbiosis and metabolic disruption correlating with severity. Elevated Klebsiella abundance suggests a pathogenic role in progression. Distinct fecal and mucosal metabolic pathway alterations provide novel insights for disease classification and therapeutic targeting.

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Publication Details

Journal
Journal of Applied Microbiology
Published
2026-03-20
DOI
https://doi.org/10.1093/jambio/lxag079
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

Klebsiella Enrichment Is Associated with Disease Severity in Ulcerative Colitis

Y Zhang, Tianqi Ren, Yingying Wu, Xin Li et al.
Journal of Applied Microbiology
Gut microbiota and health
article

Klebsiella Enrichment Is Associated with Disease Severity in Ulcerative Colitis

Y Zhang, Tianqi Ren, Yingying Wu, Xin Li, Jie Chen, Hongjie Zhang
article en

Abstract

UC demonstrates gut dysbiosis and metabolic disruption correlating with severity. Elevated Klebsiella abundance suggests a pathogenic role in progression. Distinct fecal and mucosal metabolic pathway alterations provide novel insights for disease classification and therapeutic targeting.

Journal of Applied Microbiology
Northern Jiangsu People's Hospital (CN), Nanjing Medical University (CN)
Zero hunger
Openalex Percentile: Top 14%
Gut microbiota and health
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