Nuclear YAP Activation in an Ex Vivo Murine Lung Model of Fetal Tracheal Occlusion
In this ex vivo model, tracheal occlusion upregulates nYAP in both control and hypoplastic lungs during the canalicular stage of development, suggesting a critical role of mechanosensory response molecule in CDH lung hypoplasia.
Authors
- Shaun M. Kunisaki (ORCID: https://orcid.org/0000-0002-9229-4733)
- Shelby R. Sferra (ORCID: https://orcid.org/0000-0002-8865-9103)
- Annalise Penikis
- Anne M. Sescleifer (ORCID: https://orcid.org/0000-0002-5799-1832)
- Juan Carlos Biancotti
- Latoya A. Stewart
- Wenyu Yang
Publication Details
- Journal
- Fetal Diagnosis and Therapy
- Published
- 2026-03-20
- DOI
- https://doi.org/10.1159/000551625
- Primary Topic
- Congenital Diaphragmatic Hernia Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00