Application of risk priority number of failure mode and effects analysis to drug–variant pairs for severe cutaneous adverse reactions in Korean and American populations

Drug-variant pairs with high RPN scores can be prioritized in clinical strategies to prevent SCARs in Korean and American populations. Incorporating these findings into clinical practices could ultimately contribute to the safe use of drugs.

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Publication Details

Journal
Pharmacogenetics and Genomics
Published
2026-02-16
DOI
https://doi.org/10.1097/fpc.0000000000000596
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
0.00
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article

Application of risk priority number of failure mode and effects analysis to drug–variant pairs for severe cutaneous adverse reactions in Korean and American populations

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Application of risk priority number of failure mode and effects analysis to drug–variant pairs for severe cutaneous adverse reactions in Korean and American populations

Min Ju Kang, Ha Young Jang, Hyun Kyung Lee, S. H. Oh, In-Wha Kim, Nayoung Han, Hajung Kim
article en

Abstract

Drug-variant pairs with high RPN scores can be prioritized in clinical strategies to prevent SCARs in Korean and American populations. Incorporating these findings into clinical practices could ultimately contribute to the safe use of drugs.

Pharmacogenetics and Genomics
Gachon University (KR), Seoul National University (KR), Jeju National University (KR)
Good health and well-being
Openalex Percentile: Top 15%
Drug-Induced Adverse Reactions
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