Early predictive value of maternal peripheral blood circulating immune cell counts for spontaneous preterm birth

Women with SPB exhibit features of immune imbalance characterized by elevated NK cells, elevated CD8<sup>+</sup> T cells, and a decreased CD4<sup>+</sup>/CD8<sup>+</sup> ratio. The CD4<sup>+</sup>/CD8<sup>+</sup> ratio and NK cell percentage were independently associated with SPB.

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Publication Details

Journal
The Journal of Maternal-Fetal & Neonatal Medicine
Published
2026-03-13
DOI
https://doi.org/10.1080/14767058.2026.2645739
Primary Topic
Reproductive System and Pregnancy
Type
article
Field-Weighted Citation Impact
0.00
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article

Early predictive value of maternal peripheral blood circulating immune cell counts for spontaneous preterm birth

Yan Xu, Jun Huang, ShuJuan Yang, CuiHua Zhou
The Journal of Maternal-Fetal & Neonatal Medicine
Reproductive System and Pregnancy
article

Early predictive value of maternal peripheral blood circulating immune cell counts for spontaneous preterm birth

Yan Xu, Jun Huang, ShuJuan Yang, CuiHua Zhou
article en

Abstract

Women with SPB exhibit features of immune imbalance characterized by elevated NK cells, elevated CD8<sup>+</sup> T cells, and a decreased CD4<sup>+</sup>/CD8<sup>+</sup> ratio. The CD4<sup>+</sup>/CD8<sup>+</sup> ratio and NK cell percentage were independently associated with SPB.

The Journal of Maternal-Fetal & Neonatal MedicineVol. 39(1)
Ezhou Central Hospital (CN), Obstetrics and Gynecology Hospital of Fudan University (CN), Nanchong Central Hospital (CN)
Gender equality
Openalex Percentile: Top 15%
Reproductive System and Pregnancy
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