Patient-profiled treatment responses in a large hypertension trial: a posthoc analysis of the INSIGHT study
We conclude that responses to antihypertensive treatment vary in a clinically important manner depending on the composite patient profiles. When found in other trials as well, a priori knowledge about response rates of various patient-profile treatment regimens may help choose the best treatment in individual patients and improve overall blood pressure control rates.
Authors
- Chris Palmer (ORCID: https://orcid.org/0000-0001-7940-016X)
- Morris J. Brown (ORCID: https://orcid.org/0000-0001-8409-1082)
- PW de Leeuw
- Giuseppe Mancia
- Solko W. Schalm
- Luis M. Ruilope
Institutions
- St Bartholomew's Hospital (GB)
- University of Cambridge (GB)
- Maastricht University (NL)
- Research Institute Hospital 12 de Octubre (ES)
- William Harvey Research Institute (GB)
- University of Milano-Bicocca (IT)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Journal of Hypertension
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1097/hjh.0000000000004284
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00