Comparison of human-scale MPI system concepts using a 3D arbitrary-waveform magnetic particle spectrometer

In the field of Magnetic Particle Imaging (MPI) hybrid methods are utilizing the simplicity and high SNR of magnetic particle spectrometers to complement the imaging aspect by characterizing particles and measuring system matrices for fast system calibration. In this contribution we utilized the flexibility of our 3D arbitrary-waveform magnetic particle spectrometer to measure the system functions of three MPI scanner concepts inspired by clinical-scale head-sized MPI systems. Using these system matrices we are able the compare reconstructed images under the same noise, particle and reconstruction conditions gathering first qualitative insights into the imaging properties of the different scanners.

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Publication Details

Journal
Infinite Science GmbH
Published
2025-11-03
DOI
https://doi.org/10.18416/ijmpi.2026.2603004
Primary Topic
Characterization and Applications of Magnetic Nanoparticles
Type
article
Field-Weighted Citation Impact
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article

Comparison of human-scale MPI system concepts using a 3D arbitrary-waveform magnetic particle spectrometer

Tobias A. Knopp, Niklas Hackelberg, Matthias Graeser, Justin Ackers
Infinite Science GmbH
Characterization and Applications of Magnetic Nanoparticles
article

Comparison of human-scale MPI system concepts using a 3D arbitrary-waveform magnetic particle spectrometer

Tobias A. Knopp, Niklas Hackelberg, Matthias Graeser, Justin Ackers
article en

Abstract

In the field of Magnetic Particle Imaging (MPI) hybrid methods are utilizing the simplicity and high SNR of magnetic particle spectrometers to complement the imaging aspect by characterizing particles and measuring system matrices for fast system calibration. In this contribution we utilized the flexibility of our 3D arbitrary-waveform magnetic particle spectrometer to measure the system functions of three MPI scanner concepts inspired by clinical-scale head-sized MPI systems. Using these system matrices we are able the compare reconstructed images under the same noise, particle and reconstruction conditions gathering first qualitative insights into the imaging properties of the different scanners.

Infinite Science GmbH
Universität Hamburg (DE), MSH Medical School Hamburg – University of Applied Sciences and Medical University (DE), Fraunhofer-Einrichtung für Individualisierte Medizintechnik (DE)
Openalex Percentile: Top 36%
Characterization and Applications of Magnetic Nanoparticles
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Comparison of human-scale MPI system concepts using a 3D arbitrary-waveform magnetic particle spectrometer — Tobias A. Knopp, Niklas Hackelberg, et al. · Infinite Science GmbH (2025) | TGRS Research Map | TGRS